Turkish study highlights effectiveness of third dose of COVID-19 jab

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A study in Turkey described as “one of the first in the world” by its authors found increased antibody levels in people who received their third dose of the coronavirus vaccine. The findings come amid a debate over the need for booster vaccines in the fight against the pandemic.

The study was carried out in and by Dokuz Eylül University in the western province of Izmir, with 293 health workers who work at the university’s training and research hospital and received their booster injections. The researchers measured the antibody levels of the vaccinated workers, both those who received CoronaVac injections and those who received Pfizer-BioNTech injections. The study also serves as a comparison between the two vaccines, one inactive and the other based on messenger RNA (mRNA) technology, respectively. According to the study, people who received two doses of CoronaVac, one of two vaccines available in Turkey along with the Pfizer-BioNTech vaccine, saw their antibody levels drop, which is essential for fighting potential infections in the four months after inoculation. However, 89% of them still had sufficient levels, which further increased after the recall. Speaking about the study at a press conference on Thursday, university rector Nükhet Hotar said antibody levels increased in all of the people studied who had either an inactive vaccine or an inactive vaccine. mRNA vaccine after the third dose. “Those with a third dose of CoronaVac had a 7.5-fold increase in antibody levels at least within seven days after inoculation with the booster and those with a third dose of BioNTech vaccine had a 106-fold increase. times of the same levels in the same period, “she said.

The study also showed that 4% of people were infected with COVID-19 after two doses, while only one in 293 people were infected after three doses. All recovered from the illness with mild symptoms.

Professor Bülent Kılıç, the study’s lead investigator, said he had responded to speculation about the vaccine, including “zero effectiveness of two doses of CoronaVac”. “This is apparently not true, and our study shows that people who received their two doses of CoronaVac should no longer receive two doses of Pfizer-BioNTech vaccine. According to the data we collected, a booster with the Pfizer vaccine -BioNTech is sufficient to protect people who have received two doses of CoronaVac, “Kılıç said. An additional study will be conducted in December, Kılıç added.


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